| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM50409584 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_222141 (CHEMBL822229) |
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| Ki | 17±n/a nM |
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| Citation |  Wieczerzak, E; Drabik, P; Łankiewicz, L; Oldziej, S; Grzonka, Z; Abrahamson, M; Grubb, A; Brömme, D Azapeptides structurally based upon inhibitory sites of cystatins as potent and selective inhibitors of cysteine proteases. J Med Chem45:4202-11 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM50409584 |
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| n/a |
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| Name | BDBM50409584 |
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| Synonyms: | CHEMBL2028906 |
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| Type | Small organic molecule |
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| Emp. Form. | C49H74N12O10 |
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| Mol. Mass. | 991.1863 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)NNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OC |r| |
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| Structure | 
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