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TargetTranslocator protein
LigandBDBM50118530
Substrate/Competitorn/a
Meas. Tech.ChEMBL_37200 (CHEMBL650801)
Ki 4.3±n/a nM
Citation Campiani, GRamunno, AFiorini, INacci, VMorelli, ENovellino, EGoegan, MMennini, TSullivan, SZisterer, DMWilliams, CD Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral type benzodiazepine receptors (PBR). J Med Chem45:4276-81 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Translocator protein
Name:Translocator protein
Synonyms:Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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  Blast E-value cutoff:
BDBM50118530
n/a
NameBDBM50118530
Synonyms:Azetidine-1-carboxylic acid 5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-yl ester | CHEMBL132915
TypeSmall organic molecule
Emp. Form.C22H18N2O3
Mol. Mass.358.3899
SMILESO=C(OC1=C(Oc2ccccc2-n2cccc12)c1ccccc1)N1CCC1 |t:3|
Structure
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