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TargetPeripheral-Type Benzodiazepine Receptor
LigandBDBM50118539
Substrate/Competitorn/a
Meas. Tech.ChEMBL_37198
Ki 0.23±n/a nM
Citation Campiani GRamunno AFiorini INacci VMorelli ENovellino EGoegan MMennini TSullivan SZisterer DMWilliams CD Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral type benzodiazepine receptors (PBR). J Med Chem 45:4276-81 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Peripheral-Type Benzodiazepine Receptor
Name:Benzodiazepine receptors; peripheral & central
Synonyms:Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR)
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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  Blast E-value cutoff:
BDBM50118539
n/a
NameBDBM50118539
Synonyms:CHEMBL136036 | Diethyl-carbamic acid 5-thiophen-2-yl-6-oxa-10,10b-diaza-benzo[e]azulen-4-yl ester
TypeSmall organic molecule
Emp. Form.C20H19N3O3S
Mol. Mass.381.448
SMILESCCN(CC)C(=O)OC1=C(Oc2cccnc2-n2cccc12)c1cccs1 |t:8|
Structure
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