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TargetTranslocator protein
LigandBDBM50118540
Substrate/Competitorn/a
Meas. Tech.ChEMBL_37198 (CHEMBL650799)
Ki 2.5±n/a nM
Citation Campiani, GRamunno, AFiorini, INacci, VMorelli, ENovellino, EGoegan, MMennini, TSullivan, SZisterer, DMWilliams, CD Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral type benzodiazepine receptors (PBR). J Med Chem45:4276-81 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Translocator protein
Name:Translocator protein
Synonyms:Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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  Blast E-value cutoff:
BDBM50118540
n/a
NameBDBM50118540
Synonyms:Acetic acid 5-m-tolyl-6-oxa-10b-aza-benzo[e]azulen-4-yl ester | CHEMBL135484
TypeSmall organic molecule
Emp. Form.C21H17NO3
Mol. Mass.331.3646
SMILESCC(=O)OC1=C(Oc2ccccc2-n2cccc12)c1cccc(C)c1 |t:4|
Structure
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