| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50076986 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_159288 (CHEMBL764271) |
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| IC50 | <0.200000±n/a nM |
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| Citation |  Raghavan, S; Yang, Z; Mosley, RT; Schleif, WA; Gabryelski, L; Olsen, DB; Stahlhut, M; Kuo, LC; Emini, EA; Chapman, KT; Tata, JR Combinatorial library of indinavir analogues: replacement for the aminoindanol at P2'. Bioorg Med Chem Lett12:2855-8 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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|
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| BDBM50076986 |
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| n/a |
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| Name | BDBM50076986 |
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| Synonyms: | CHEMBL95733 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H50N6O6S3 |
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| Mol. Mass. | 795.046 |
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| SMILES | CSc1nccc(n1)-c1ccc(s1)S(=O)(=O)N1CCN(C[C@H](O)C[C@@H](Cc2ccccc2)C(=O)NCc2c(C)cc(O)cc2C)[C@H](C1)C(=O)NC(C)(C)C |
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| Structure | 
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