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TargetPeripheral-Type Benzodiazepine Receptor
LigandBDBM50007664
Substrate/Competitorn/a
Meas. Tech.ChEBML_37065
Ki 438±n/a nM
Citation Pacofsky GJStafford JACox RFCowan JRDorsey GFGonzales SSKaldor IKoszalka GWLovell GGMcIntyre MSTidwell JHTodd DWhitesell GWiard RPFeldman PL Relating the structure, activity, and physical properties of ultrashort-acting benzodiazepine receptor agonists. Bioorg Med Chem Lett 12:3219-22 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Peripheral-Type Benzodiazepine Receptor
Name:Benzodiazepine receptors; peripheral & central
Synonyms:Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR)
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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  Blast E-value cutoff:
BDBM50007664
n/a
NameBDBM50007664
Synonyms:7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepin-4-oxide | 7-chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide | CDP | CHEMBL451 | CHLORDIAZEPOXIDE | clopoxide | methaminodiazepoxide
TypeSmall organic molecule
Emp. Form.C16H14ClN3O
Mol. Mass.299.755
SMILESCNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=[N+]([O-])C1 |t:2,19|
Structure
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