Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPeripheral-Type Benzodiazepine Receptor
LigandBDBM50120358
Substrate/Competitorn/a
Meas. Tech.ChEBML_37065
Ki 98±n/a nM
Citation Pacofsky GJStafford JACox RFCowan JRDorsey GFGonzales SSKaldor IKoszalka GWLovell GGMcIntyre MSTidwell JHTodd DWhitesell GWiard RPFeldman PL Relating the structure, activity, and physical properties of ultrashort-acting benzodiazepine receptor agonists. Bioorg Med Chem Lett 12:3219-22 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Peripheral-Type Benzodiazepine Receptor
Name:Benzodiazepine receptors; peripheral & central
Synonyms:Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR)
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50120358
n/a
NameBDBM50120358
Synonyms:3-((S)-8-Chloro-1-methyl-6-pyridin-2-yl-4H-3,5,10b-triaza-benzo[e]azulen-4-yl)-propionic acid methyl ester | CHEMBL322701
TypeSmall organic molecule
Emp. Form.C21H19ClN4O2
Mol. Mass.394.854
SMILESCOC(=O)CC[C@@H]1N=C(c2ccccn2)c2cc(Cl)ccc2-n2c(C)cnc12 |t:7|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: