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TargetPeripheral-Type Benzodiazepine Receptor
LigandBDBM50120360
Substrate/Competitorn/a
Meas. Tech.ChEBML_37065
Ki 8±n/a nM
Citation Pacofsky GJStafford JACox RFCowan JRDorsey GFGonzales SSKaldor IKoszalka GWLovell GGMcIntyre MSTidwell JHTodd DWhitesell GWiard RPFeldman PL Relating the structure, activity, and physical properties of ultrashort-acting benzodiazepine receptor agonists. Bioorg Med Chem Lett 12:3219-22 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Peripheral-Type Benzodiazepine Receptor
Name:Benzodiazepine receptors; peripheral & central
Synonyms:Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR)
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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  Blast E-value cutoff:
BDBM50120360
n/a
NameBDBM50120360
Synonyms:3-[(S)-8-Chloro-6-(2-fluoro-phenyl)-1-methyl-4H-3,5,10b-triaza-benzo[e]azulen-4-yl]-propionic acid methyl ester | CHEMBL321824
TypeSmall organic molecule
Emp. Form.C22H19ClFN3O2
Mol. Mass.411.857
SMILESCOC(=O)CC[C@@H]1N=C(c2ccccc2F)c2cc(Cl)ccc2-n2c(C)cnc12 |t:7|
Structure
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