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TargetTranslocator protein
LigandBDBM50120359
Substrate/Competitorn/a
Meas. Tech.ChEBML_37065
Ki 60±n/a nM
Citation Pacofsky, GJStafford, JACox, RFCowan, JRDorsey, GFGonzales, SSKaldor, IKoszalka, GWLovell, GGMcIntyre, MSTidwell, JHTodd, DWhitesell, GWiard, RPFeldman, PL Relating the structure, activity, and physical properties of ultrashort-acting benzodiazepine receptor agonists. Bioorg Med Chem Lett12:3219-22 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Translocator protein
Name:Translocator protein
Synonyms:Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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  Blast E-value cutoff:
BDBM50120359
n/a
NameBDBM50120359
Synonyms:3-((S)-8-Chloro-2-methyl-6-pyridin-2-yl-4H-3,5,10b-triaza-benzo[e]azulen-4-yl)-propionic acid methyl ester | CHEMBL325802
TypeSmall organic molecule
Emp. Form.C21H19ClN4O2
Mol. Mass.394.854
SMILESCOC(=O)CC[C@@H]1N=C(c2ccccn2)c2cc(Cl)ccc2-n2cc(C)nc12 |t:7|
Structure
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