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TargetFibroblast growth factor 2
LigandBDBM50421574
Substrate/Competitorn/a
Meas. Tech.ChEMBL_70468 (CHEMBL676959)
IC50 340±n/a nM
Citation Murphy, PVPitt, NO'Brien, AEnright, PMDunne, AWilson, SJDuane, RMO'Boyle, KM Identification of novel inhibitors of fibroblast growth factor (FGF-2) binding to heparin and endothelial cell survival from a structurally diverse carbohybrid library. Bioorg Med Chem Lett12:3287-90 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Fibroblast growth factor 2
Name:Fibroblast growth factor 2
Synonyms:Basic fibroblast growth factor | FGF-2 | FGF2 | FGF2_HUMAN | FGFB | Fibroblast growth factor 2 (bFGF) | Fibroblast growth factor receptor 2 (FGF-2) | HBGF-2 | Heparin-binding growth factor 2
Type:Protein
Mol. Mass.:30803.89
Organism:Homo sapiens (Human)
Description:P09038
Residue:288
Sequence:
MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAA
GSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAA
PAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDG
RVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERL
ESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
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  Blast E-value cutoff:
BDBM50421574
n/a
NameBDBM50421574
Synonyms:CHEMBL2303729
TypeSmall organic molecule
Emp. Form.C12H17NO9
Mol. Mass.319.2647
SMILESO[C@@H]1[C@H](O)[C@H](OCCN2C(=O)CCC2=O)O[C@H]([C@H]1O)C(O)=O |r|
Structure
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