| Reaction Details |
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 | Report a problem with these data |
| Target | Peptide deformylase, mitochondrial |
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| Ligand | BDBM50121440 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_154177 (CHEMBL762381) |
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| IC50 | 200±n/a nM |
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| Citation |  Smith, HK; Beckett, RP; Clements, JM; Doel, S; East, SP; Launchbury, SB; Pratt, LM; Spavold, ZM; Thomas, W; Todd, RS; Whittaker, M Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group. Bioorg Med Chem Lett12:3595-9 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptide deformylase, mitochondrial |
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| Name: | Peptide deformylase, mitochondrial |
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| Synonyms: | DEFM_HUMAN | PDF | PDF1A | Peptide deformylase mitochondrial | Peptide deformylase, mitochondrial | Polypeptide deformylase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27023.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_154318 |
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| Residue: | 243 |
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| Sequence: | MARLWGALSLWPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPP
EPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPR
QVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLA
CVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMK
VND
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|
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| BDBM50121440 |
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| n/a |
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| Name | BDBM50121440 |
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| Synonyms: | (R)-3-((S)-1-Dimethylcarbamoyl-2,2-dimethyl-propylcarbamoyl)-heptanoic acid | CHEMBL422256 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H30N2O4 |
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| Mol. Mass. | 314.4204 |
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| SMILES | CCCC[C@H](CC(O)=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C |
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| Structure | 
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