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TargetPeptide deformylase, mitochondrial
LigandBDBM50121441
Substrate/Competitorn/a
Meas. Tech.ChEMBL_154177 (CHEMBL762381)
IC50>1000±n/a nM
Citation Smith, HKBeckett, RPClements, JMDoel, SEast, SPLaunchbury, SBPratt, LMSpavold, ZMThomas, WTodd, RSWhittaker, M Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group. Bioorg Med Chem Lett12:3595-9 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Peptide deformylase, mitochondrial
Name:Peptide deformylase, mitochondrial
Synonyms:DEFM_HUMAN | PDF | PDF1A | Peptide deformylase mitochondrial | Peptide deformylase, mitochondrial | Polypeptide deformylase
Type:PROTEIN
Mol. Mass.:27023.25
Organism:Homo sapiens (Human)
Description:ChEMBL_154318
Residue:243
Sequence:
MARLWGALSLWPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPP
EPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPR
QVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLA
CVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMK
VND
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  Blast E-value cutoff:
BDBM50121441
n/a
NameBDBM50121441
Synonyms:(R)-2-(N-Hydroxycarbamimidoylmethyl)-hexanoic acid ((S)-1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide | CHEMBL120392
TypeSmall organic molecule
Emp. Form.C16H32N4O3
Mol. Mass.328.4503
SMILESCCCCC(CC(=N)NO)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C
Structure
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