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TargetGag-Pol polyprotein [489-587]
LigandBDBM50121735
Substrate/Competitorn/a
Meas. Tech.ChEBML_79946
Ki 3±n/a nM
Citation Hidaka, KKimura, THayashi, YMcDaniel, KFDekhtyar, TColletti, LKiso, Y Design and synthesis of pseudo-symmetric HIV protease inhibitors containing a novel hydroxymethylcarbonyl (HMC)-hydrazide isostere. Bioorg Med Chem Lett13:93-6 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50121735
n/a
NameBDBM50121735
Synonyms:CHEMBL367679 | KNI-1277 | N-[(S)-3-[N-Benzyl-N'-(3-hydroxy-2-methyl-benzoyl)-hydrazino]-2-hydroxy-3-oxo-1-((S)-phenylmethyl)-propyl]-2-(2,6-dimethyl-phenoxy)-acetamide
TypeSmall organic molecule
Emp. Form.C35H37N3O6
Mol. Mass.595.6848
SMILESCc1cccc(C)c1OCC(=O)N[C@@H](Cc1ccccc1)[C@H](O)C(=O)N(Cc1ccccc1)NC(=O)c1cccc(O)c1C
Structure
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