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TargetCathepsin B
LigandBDBM50121901
Substrate/Competitorn/a
Meas. Tech.ChEBML_47599
IC50 470±n/a nM
Citation Zhou NEGuo DThomas GReddy AVKaleta JPurisima EMenard RMicetich RGSingh R 3-Acylamino-azetidin-2-one as a novel class of cysteine proteases inhibitors. Bioorg Med Chem Lett 13:139-41 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Cathepsin B
Name:Cathepsin B
Synonyms:n/a
Type:Protein
Mol. Mass.:37463.53
Organism:Rattus norvegicus
Description:P00787
Residue:339
Sequence:
MWWSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCG
TVLGGPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDR
ICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCL
PYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIM
AEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSW
NVDWGDNGFFKILRGENHCGIESEIVAGIPRTQQYWGRF
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  Blast E-value cutoff:
BDBM50121901
n/a
NameBDBM50121901
Synonyms:Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester | CHEMBL417303
TypeSmall organic molecule
Emp. Form.C22H23N3O6
Mol. Mass.425.4345
SMILESCC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1
Structure
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