| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin B |
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| Ligand | BDBM50121903 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_47599 |
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| IC50 | 39700±n/a nM |
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| Citation |  Zhou, NE; Guo, D; Thomas, G; Reddy, AV; Kaleta, J; Purisima, E; Menard, R; Micetich, RG; Singh, R 3-Acylamino-azetidin-2-one as a novel class of cysteine proteases inhibitors. Bioorg Med Chem Lett13:139-41 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin B |
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| Name: | Cathepsin B |
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| Synonyms: | CATB_RAT | Ctsb |
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| Type: | Protein |
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| Mol. Mass.: | 37463.53 |
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| Organism: | Rattus norvegicus |
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| Description: | P00787 |
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| Residue: | 339 |
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| Sequence: | MWWSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCG
TVLGGPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDR
ICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCL
PYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIM
AEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSW
NVDWGDNGFFKILRGENHCGIESEIVAGIPRTQQYWGRF
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| BDBM50121903 |
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| n/a |
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| Name | BDBM50121903 |
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| Synonyms: | CHEMBL31272 | [(S)-1-((3R,4R)-2-Oxo-4-phenylsulfanyl-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C26H25N3O4S |
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| Mol. Mass. | 475.559 |
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| SMILES | O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@H]1[C@H](NC1=O)Sc1ccccc1)OCc1ccccc1 |
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| Structure | 
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