| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50121972 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90861 (CHEMBL699296) |
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| IC50 | 8000±n/a nM |
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| Citation |  Neamati, N; Lin, Z; Karki, RG; Orr, A; Cowansage, K; Strumberg, D; Pais, GC; Voigt, JH; Nicklaus, MC; Winslow, HE; Zhao, H; Turpin, JA; Yi, J; Skalka, AM; Burke, TR; Pommier, Y Metal-dependent inhibition of HIV-1 integrase. J Med Chem45:5661-70 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50121972 |
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| n/a |
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| Name | BDBM50121972 |
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| Synonyms: | CHEMBL157373 | Compound 3 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H22N4O4S4 |
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| Mol. Mass. | 606.759 |
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| SMILES | Sc1ccccc1C(=O)NNC(=O)c1ccccc1SSc1ccccc1C(=O)NNC(=O)c1ccccc1S |
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| Structure | 
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