Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50121971 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_159619 (CHEMBL760100) |
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IC50 | >100000±n/a nM |
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Citation | Neamati, N; Lin, Z; Karki, RG; Orr, A; Cowansage, K; Strumberg, D; Pais, GC; Voigt, JH; Nicklaus, MC; Winslow, HE; Zhao, H; Turpin, JA; Yi, J; Skalka, AM; Burke, TR; Pommier, Y Metal-dependent inhibition of HIV-1 integrase. J Med Chem45:5661-70 (2002) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50121971 |
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n/a |
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Name | BDBM50121971 |
Synonyms: | 2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hydrazide | CHEMBL157428 | bis(thiosalicyl)hydrazide |
Type | Small organic molecule |
Emp. Form. | C14H12N2O2S2 |
Mol. Mass. | 304.387 |
SMILES | Sc1ccccc1C(=O)NNC(=O)c1ccccc1S |
Structure |
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