| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50122716 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1559 (CHEMBL616380) |
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| IC50 | 9100.0±n/a nM |
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| Citation |  Hinschberger, A; Butt, S; Lelong, V; Boulouard, M; Dumuis, A; Dauphin, F; Bureau, R; Pfeiffer, B; Renard, P; Rault, S New benzo[h][1,6]naphthyridine and azepino[3,2-c]quinoline derivatives as selective antagonists of 5-HT4 receptors: binding profile and pharmacological characterization. J Med Chem46:138-47 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT1A | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_MOUSE | Gpcr18 | Htr1a | Serotonin 1a (5-HT1a) receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 46192.09 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q64264 |
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| Residue: | 421 |
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| Sequence: | MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGT
SFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGN
SKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
R
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| BDBM50122716 |
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| n/a |
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| Name | BDBM50122716 |
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| Synonyms: | 5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahydro-benzo[h][1,6]naphthyridine | CHEMBL35226 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H29N3O |
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| Mol. Mass. | 339.4745 |
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| SMILES | CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 |
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| Structure | 
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