| Reaction Details |
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 | Report a problem with these data |
| Target | Purine nucleoside phosphorylase |
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| Ligand | BDBM50422435 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_162004 (CHEMBL764175) |
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| Ki | 0.042000±n/a nM |
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| Citation |  Evans, GB; Furneaux, RH; Gainsford, GJ; Hanson, JC; Kicska, GA; Sauve, AA; Schramm, VL; Tyler, PC 8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases. J Med Chem46:155-60 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Purine nucleoside phosphorylase |
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| Name: | Purine nucleoside phosphorylase |
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| Synonyms: | Inosine phosphorylase | NP | PNP | PNPH_BOVIN | Purine Nucleoside Phosphorylase (PNP) | Purine nucleoside phosphorylase |
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| Type: | Enzyme |
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| Mol. Mass.: | 32035.18 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 289 |
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| Sequence: | MANGYTYEDYQDTAKWLLSHTEQRPQVAVICGSGLGGLVNKLTQAQTFDYSEIPNFPEST
VPGHAGRLVFGILNGRACVMMQGRFHMYEGYPFWKVTFPVRVFRLLGVETLVVTNAAGGL
NPNFEVGDIMLIRDHINLPGFSGENPLRGPNEERFGVRFPAMSDAYDRDMRQKAHSTWKQ
MGEQRELQEGTYVMLGGPNFETVAECRLLRNLGADAVGMSTVPEVIVARHCGLRVFGFSL
ITNKVIMDYESQGKANHEEVLEAGKQAAQKLEQFVSLLMASIPVSGHTG
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| BDBM50422435 |
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| n/a |
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| Name | BDBM50422435 |
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| Synonyms: | CHEMBL2311112 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H13N5O4 |
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| Mol. Mass. | 267.2413 |
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| SMILES | OC[C@H]1N[C@H]([C@H](O)[C@@H]1O)c1[nH]nc2c1nc[nH]c2=O |
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| Structure | 
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