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TargetPurine Nucleoside Phosphorylase (PNP)
LigandBDBM50422435
Substrate/Competitorn/a
Meas. Tech.ChEMBL_162004
Ki 0.042000±n/a nM
Citation Evans GBFurneaux RHGainsford GJHanson JCKicska GASauve AASchramm VLTyler PC 8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases. J Med Chem 46:155-60 (2002) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Purine Nucleoside Phosphorylase (PNP)
Name:Purine nucleoside phosphorylase
Synonyms:Inosine phosphorylase
Type:Enzyme
Mol. Mass.:32035.18
Organism:Bos taurus (bovine)
Description:n/a
Residue:289
Sequence:
MANGYTYEDYQDTAKWLLSHTEQRPQVAVICGSGLGGLVNKLTQAQTFDYSEIPNFPEST
VPGHAGRLVFGILNGRACVMMQGRFHMYEGYPFWKVTFPVRVFRLLGVETLVVTNAAGGL
NPNFEVGDIMLIRDHINLPGFSGENPLRGPNEERFGVRFPAMSDAYDRDMRQKAHSTWKQ
MGEQRELQEGTYVMLGGPNFETVAECRLLRNLGADAVGMSTVPEVIVARHCGLRVFGFSL
ITNKVIMDYESQGKANHEEVLEAGKQAAQKLEQFVSLLMASIPVSGHTG
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  Blast E-value cutoff:
BDBM50422435
n/a
NameBDBM50422435
Synonyms:CHEMBL2311112
TypeSmall organic molecule
Emp. Form.C10H13N5O4
Mol. Mass.267.2413
SMILESOC[C@H]1N[C@H]([C@H](O)[C@@H]1O)c1[nH]nc2c1nc[nH]c2=O
Structure
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