Ki Summary

Reaction Details

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Target

Carnitine O-palmitoyltransferase 1, muscle isoform

Ligand

BDBM50122833

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_46329 (CHEMBL874517)

IC50

80100.0±n/a nM

Citation

Giannessi, F; Pessotto, P; Tassoni, E; Chiodi, P; Conti, R; De Angelis, F; Dell'Uomo, N; Catini, R; Deias, R; Tinti, MO; Carminati, P; Arduini, A Discovery of a long-chain carbamoyl aminocarnitine derivative, a reversible carnitine palmitoyltransferase inhibitor with antiketotic and antidiabetic activity. J Med Chem46:303-9 (2003) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Carnitine O-palmitoyltransferase 1, muscle isoform

Name:

Carnitine O-palmitoyltransferase 1, muscle isoform

Synonyms:

CPT1B_RAT | Carnitine palmitoyltransferase 1B | Cpt1b

Type:

PROTEIN

Mol. Mass.:

88241.28

Organism:

Rattus norvegicus

Description:

ChEMBL_887447

Residue:

772

Sequence:

MAEAHQAVAFQFTVTPDGVDFRLSREALRHIYLSGINSWKKRLIRIKNGILRGVYPGSPT
SWLVVVMATVGSNYCKVDISMGLVHCIQRCLPTRYGSYGTPQTETLLSMVIFSTGVWATG
IFLFRQTLKLLLSYHGWMFEMHSKTSHATKIWAICVRLLSSRRPMLYSFQTSLPKLPVPS
VPATIHRYLDSVRPLLDDEAYFRMESLAKEFQDKIAPRLQKYLVLKSWWATNYVSDWWEE
YVYLRGRSPIMVNSNYYAMDFVLIKNTSQQAARLGNTVHAMIMYRRKLDREEIKPVMALG
MVPMCSYQMERMFNTTRIPGKETDLLQHLSESRHVAVYHKGRFFKVWLYEGSCLLKPRDL
EMQFQRILDDTSPPQPGEEKLAALTAGGRVEWAEARQKFFSSGKNKMSLDTIERAAFFVA
LDEDSHCYNPDDEASLSLYGKSLLHGNCYNRWFDKSFTLISCKNGQLGLNTEHSWADAPI
IGHLWEFVLATDTFHLGYTETGHCVGEPNTKLPPPQRMQWDIPEQCQTAIENSYQVAKAL
ADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDKGKFCLTYEASMTRMFREG
RTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKASEKHQNMYRLAMTGAGIDRHLFCL
YIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQFQICMFDPKQYPNHLGAGGGFGPVADHGY
GVSYMIAGENTMFFHVSSKLSSSETNALRFGNHIRQALLDIADLFKISKTDS

BDBM50122833

n/a

Name

BDBM50122833

Synonyms:

(3-Carboxy-2-octyloxycarbonylamino-propyl)-trimethyl-ammonium | CHEMBL105596

Type

Small organic molecule

Emp. Form.

C16H32N2O4

Mol. Mass.

316.4363

SMILES

CCCCCCCCOC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C

Structure