| Reaction Details |
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 | Report a problem with these data |
| Target | Carnitine O-palmitoyltransferase 1, muscle isoform |
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| Ligand | BDBM50101598 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_46329 (CHEMBL874517) |
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| IC50 | >10000±n/a nM |
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| Citation |  Giannessi, F; Pessotto, P; Tassoni, E; Chiodi, P; Conti, R; De Angelis, F; Dell'Uomo, N; Catini, R; Deias, R; Tinti, MO; Carminati, P; Arduini, A Discovery of a long-chain carbamoyl aminocarnitine derivative, a reversible carnitine palmitoyltransferase inhibitor with antiketotic and antidiabetic activity. J Med Chem46:303-9 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carnitine O-palmitoyltransferase 1, muscle isoform |
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| Name: | Carnitine O-palmitoyltransferase 1, muscle isoform |
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| Synonyms: | CPT1B_RAT | Carnitine palmitoyltransferase 1B | Cpt1b |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88241.28 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_887447 |
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| Residue: | 772 |
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| Sequence: | MAEAHQAVAFQFTVTPDGVDFRLSREALRHIYLSGINSWKKRLIRIKNGILRGVYPGSPT
SWLVVVMATVGSNYCKVDISMGLVHCIQRCLPTRYGSYGTPQTETLLSMVIFSTGVWATG
IFLFRQTLKLLLSYHGWMFEMHSKTSHATKIWAICVRLLSSRRPMLYSFQTSLPKLPVPS
VPATIHRYLDSVRPLLDDEAYFRMESLAKEFQDKIAPRLQKYLVLKSWWATNYVSDWWEE
YVYLRGRSPIMVNSNYYAMDFVLIKNTSQQAARLGNTVHAMIMYRRKLDREEIKPVMALG
MVPMCSYQMERMFNTTRIPGKETDLLQHLSESRHVAVYHKGRFFKVWLYEGSCLLKPRDL
EMQFQRILDDTSPPQPGEEKLAALTAGGRVEWAEARQKFFSSGKNKMSLDTIERAAFFVA
LDEDSHCYNPDDEASLSLYGKSLLHGNCYNRWFDKSFTLISCKNGQLGLNTEHSWADAPI
IGHLWEFVLATDTFHLGYTETGHCVGEPNTKLPPPQRMQWDIPEQCQTAIENSYQVAKAL
ADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDKGKFCLTYEASMTRMFREG
RTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKASEKHQNMYRLAMTGAGIDRHLFCL
YIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQFQICMFDPKQYPNHLGAGGGFGPVADHGY
GVSYMIAGENTMFFHVSSKLSSSETNALRFGNHIRQALLDIADLFKISKTDS
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| BDBM50101598 |
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| n/a |
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| Name | BDBM50101598 |
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| Synonyms: | CHEMBL307495 | [3-Carboxy-2-(dodecane-1-sulfonylamino)-propyl]-trimethyl-ammonium |
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| Type | Small organic molecule |
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| Emp. Form. | C19H40N2O4S |
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| Mol. Mass. | 392.597 |
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| SMILES | CCCCCCCCCCCCS(=O)(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C |
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| Structure | 
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