| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Chorismate synthase |
|---|
| Ligand | BDBM50123102 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_49434 |
|---|
| IC50 | 10700±n/a nM |
|---|
| Citation |  Thomas, MG; Lawson, C; Allanson, NM; Leslie, BW; Bottomley, JR; McBride, A; Olusanya, OA A series of 2(Z)-2-benzylidene-6,7-dihydroxybenzofuran-3[2H]-ones as inhibitors of chorismate synthase. Bioorg Med Chem Lett13:423-6 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Chorismate synthase |
|---|
| Name: | Chorismate synthase |
|---|
| Synonyms: | AROC_STRPN | aroC |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 42869.22 |
|---|
| Organism: | Streptococcus pneumoniae |
|---|
| Description: | ChEMBL_49433 |
|---|
| Residue: | 388 |
|---|
| Sequence: | MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYGRGGRMKIENDQVVFTS
GVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRKITHPRPGHADLVGGIKYR
FDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANHVVVFGGKEIDVPENLTVAEI
KQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVVETVVGGVPVGLGSYVQWDRKLD
ARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEILWSKEDGYTRRTNNLGGFEGGMTN
GQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKATVERSDPTALPAAGMVMEAVVATVLAQ
EILEKFSSDNLEELKEAVAKHRDYTKNY
|
|
|
|---|
| BDBM50123102 |
|---|
| n/a |
|---|
| Name | BDBM50123102 |
|---|
| Synonyms: | 2-[6,7-Dihydroxy-3-oxo-3H-benzofuran-(2E)-ylidenemethyl]-benzoic acid | CHEMBL131915 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H10O6 |
|---|
| Mol. Mass. | 298.247 |
|---|
| SMILES | OC(=O)c1ccccc1\C=C1\Oc2c(ccc(O)c2O)C1=O |
|---|
| Structure | 
|
|---|
Search and Browse
