| Reaction Details |
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 | Report a problem with these data |
| Target | Anionic trypsin-2 |
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| Ligand | BDBM50123413 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_213052 |
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| IC50 | 167±n/a nM |
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| Citation |  Huang, W; Zhang, P; Zuckett, JF; Wang, L; Woolfrey, J; Song, Y; Jia, ZJ; Clizbe, LA; Su, T; Tran, K; Huang, B; Wong, P; Sinha, U; Park, G; Reed, A; Malinowski, J; Hollenbach, SJ; Scarborough, RM; Zhu, BY Design, synthesis and structure-activity relationships of benzoxazinone-based factor Xa inhibitors. Bioorg Med Chem Lett13:561-6 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Anionic trypsin-2 |
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| Name: | Anionic trypsin-2 |
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| Synonyms: | Prss2 | TRY2_RAT | Try2 | Trypsin II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26220.44 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_213052 |
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| Residue: | 246 |
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| Sequence: | MRALLFLALVGAAVAFPVDDDDKIVGGYTCQENSVPYQVSLNSGYHFCGGSLINDQWVVS
AAHCYKSRIQVRLGEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLN
ARVATVALPSSCAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKIT
DNMVCVGFLEGGKDSCQGDSGGPVVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQ
DTIAAN
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| BDBM50123413 |
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| n/a |
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| Name | BDBM50123413 |
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| Synonyms: | 2-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phenyl}-methanesulfonyl-amino)-methyl]-1-methyl-1H-indole-5-carboxamidine | CHEMBL345785 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H32N6O3S |
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| Mol. Mass. | 496.625 |
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| SMILES | CC(=N)N1CCC(CC1)Oc1ccc(cc1)N(Cc1cc2cc(ccc2n1C)C(N)=N)S(C)(=O)=O |
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| Structure | 
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