| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50123627 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60330 (CHEMBL672802) |
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| Ki | 3±n/a nM |
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| Citation |  Venhuis, BJ; Dijkstra, D; Wustrow, DJ; Meltzer, LT; Wise, LD; Johnson, SJ; Heffner, TG; Wikström, HV Orally active analogues of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one: synthesis and pharmacological activity. J Med Chem46:584-90 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | D(1A) dopamine receptor | D1AR | DOPAMINE D1 | DRD1 | DRD1_BOVIN | Dopamine receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49330.65 |
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| Organism: | BOVINE |
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| Description: | DOPAMINE D1 DRD1 BOVINE::Q95136 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLG
KTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKN
CQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGS
GETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50123627 |
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| n/a |
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| Name | BDBM50123627 |
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| Synonyms: | (S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | CHEMBL155596 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H25NO2 |
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| Mol. Mass. | 263.3752 |
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| SMILES | CCCN(CCC)[C@H]1CCc2c(C1)ccc(O)c2O |
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| Structure | 
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