| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
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| Ligand | BDBM50123735 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_144130 (CHEMBL750103) |
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| Ki | 33±n/a nM |
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| Citation |  Sato, N; Takahashi, T; Shibata, T; Haga, Y; Sakuraba, A; Hirose, M; Sato, M; Nonoshita, K; Koike, Y; Kitazawa, H; Fujino, N; Ishii, Y; Ishihara, A; Kanatani, A; Fukami, T Design and synthesis of the potent, orally available, brain-penetrable arylpyrazole class of neuropeptide Y5 receptor antagonists. J Med Chem46:666-9 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 5 |
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| Name: | Neuropeptide Y receptor type 5 |
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| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 50746.64 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15761 |
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| Residue: | 445 |
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| Sequence: | MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL
LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP
ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK
KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL
NPILYGFLNNGIKADLVSLIHCLHM
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| BDBM50123735 |
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| n/a |
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| Name | BDBM50123735 |
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| Synonyms: | CHEMBL160443 | Indan-2-carboxylic acid [5-(3,4-dimethoxy-phenyl)-1H-pyrazol-3-yl]-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21N3O3 |
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| Mol. Mass. | 363.4097 |
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| SMILES | COc1ccc(cc1OC)-c1cc(NC(=O)C2Cc3ccccc3C2)[nH]n1 |
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| Structure | 
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