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TargetNPY5R
LigandBDBM50123737
Substrate/Competitorn/a
Meas. Tech.ChEMBL_144136
Ki 1.7±n/a nM
Citation Elliott RLOliver RMHammond MPatterson TAShe LHargrove DMMartin KAMaurer TSKalvass JCMorgan BPDaSilva-Jardine PAStevenson RWMack CMCassella JV In vitro and in vivo characterization of 3-[2-[6-(2-tert-butoxyethoxy)pyridin-3-yl]-1H-imidazol-4-yl]benzonitrile hydrochloride salt, a potent and selective NPY5 receptor antagonist. J Med Chem 46:670-3 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
NPY5R
Name:Neuropeptide Y receptor type 5
Synonyms:NPY-Y5 | Neuropeptide Y receptor type 5
Type:Enzyme Catalytic Domain
Mol. Mass.:50435.58
Organism:Rat 6B
Description:NPY-Y5 NPY5R Rat 6B::Q63634
Residue:445
Sequence:
MEFKLEEHFNKTFVTENNTAAARNAAFPAWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNL
LILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSHKENRLEENEMINLTLQPSKKSRNQAKTPSTQKWSYSFIRKHRRRYSKKTACVLPAP
AGPSQGKHLAVPENPASVRSQLSPSSKVIPGVPICFEVKPEESSDAHEMRVKRSITRIKK
RSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLN
PILYGFLNNGIKADLRALIHCLHMS
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  Blast E-value cutoff:
BDBM50123737
n/a
NameBDBM50123737
Synonyms:3-{2-[6-(2-tert-Butoxy-ethoxy)-pyridin-3-yl]-3H-imidazol-4-yl}-benzonitrile | CHEMBL161724
TypeSmall organic molecule
Emp. Form.C21H22N4O2
Mol. Mass.362.425
SMILESCC(C)(C)OCCOc1ccc(cn1)-c1nc(c[nH]1)-c1cccc(c1)C#N
Structure
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