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TargetDelta-type opioid receptor
LigandBDBM50123991
Substrate/Competitorn/a
Meas. Tech.ChEMBL_147150 (CHEMBL758175)
Ki 170±n/a nM
Citation Wentland, MPYe, YCioffi, CLLou, RZhou, QXu, GDuan, WDehnhardt, CMSun, XCohen, DJBidlack, JM Syntheses and opioid receptor binding affinities of 8-amino-2,6-methano-3-benzazocines. J Med Chem46:838-49 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Delta-type opioid receptor
Synonyms:D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50123991
n/a
NameBDBM50123991
Synonyms:17-cyclopropylmethyl-1,20-dimethyl-(1S,20R)-5,17-diazapentacyclo[14.3.1.02,14.04,12.06,11]icosa-2(14),3,6(11),7,9,12-hexaene | CHEMBL352365
TypeSmall organic molecule
Emp. Form.C24H28N2
Mol. Mass.344.4925
SMILESC[C@H]1C2Cc3cc4c(cc3[C@@]1(C)CCN2CC1CC1)[nH]c1ccccc41 |TLB:8:9:1:14.12.13,15:14:1:9.4.3|
Structure
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