| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50124719 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157538 |
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| Ki | 0.190000±n/a nM |
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| Citation |  Kaltenbach, RF; Patel, M; Waltermire, RE; Harris, GD; Stone, BR; Klabe, RM; Garber, S; Bacheler, LT; Cordova, BC; Logue, K; Wright, MR; Erickson-Viitanen, S; Trainor, GL Synthesis, antiviral activity and pharmacokinetics of P1/P1' substituted 3-aminoindazole cyclic urea HIV protease inhibitors. Bioorg Med Chem Lett13:605-8 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50124719 |
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| n/a |
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| Name | BDBM50124719 |
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| Synonyms: | (4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3-butyl-4,7-bis-(3,5-dimethyl-benzyl)-5,6-dihydroxy-[1,3]diazepan-2-one | CHEMBL442770 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H45N5O3 |
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| Mol. Mass. | 583.7635 |
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| SMILES | CCCCN1[C@H](Cc2cc(C)cc(C)c2)[C@H](O)[C@@H](O)[C@@H](Cc2cc(C)cc(C)c2)N(Cc2ccc3[nH]nc(N)c3c2)C1=O |
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| Structure | 
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