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Target5-hydroxytryptamine receptor 2A
LigandBDBM50222897
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2521
Ki 43±n/a nM
Citation Forbes ITCooper DGDodds EKDouglas SEGribble ADIfe RJLightfoot APMeeson MCampbell LPColeman TRiley GJThomas DR Identification of a novel series of selective 5-HT7 receptor antagonists. Bioorg Med Chem Lett 13:1055-8 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 2A
Name:Dopamine D2 receptor and serotonin 2a receptor
Synonyms:5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | HTR2 | HTR2A | Serotonin receptor 2A
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52607.65
Organism:Homo sapiens (Human)
Description:n/a
Residue:471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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  Blast E-value cutoff:
BDBM50222897
n/a
NameBDBM50222897
Synonyms:CHEMBL9446
TypeSmall organic molecule
Emp. Form.C25H28FN3O2
Mol. Mass.421.5071
SMILESFc1ccc2N(C3CCN(CCN4CCCc5ccccc5C4=O)CC3)C(=O)Cc2c1
Structure
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