| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
|---|
| Ligand | BDBM9019 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_105255 |
|---|
| IC50 | 0.300000±n/a nM |
|---|
| Citation |  Mattson, RJ; Catt, JD; Keavy, D; Sloan, CP; Epperson, J; Gao, Q; Hodges, DB; Iben, L; Mahle, CD; Ryan, E; Yocca, FD Indanyl piperazines as melatonergic MT2 selective agents. Bioorg Med Chem Lett13:1199-202 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melatonin receptor type 1B |
|---|
| Name: | Melatonin receptor type 1B |
|---|
| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40203.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P49286 |
|---|
| Residue: | 362 |
|---|
| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
|
|
|
|---|
| BDBM9019 |
|---|
| n/a |
|---|
| Name | BDBM9019 |
|---|
| Synonyms: | CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H16N2O2 |
|---|
| Mol. Mass. | 232.2783 |
|---|
| SMILES | COc1ccc2[nH]cc(CCNC(C)=O)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
