| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50125754 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105097 (CHEMBL714104) |
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| Ki | 0.5±n/a nM |
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| Citation |  Descamps-François, C; Yous, S; Chavatte, P; Audinot, V; Bonnaud, A; Boutin, JA; Delagrange, P; Bennejean, C; Renard, P; Lesieur, D Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands. J Med Chem46:1127-9 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50125754 |
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| n/a |
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| Name | BDBM50125754 |
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| Synonyms: | CHEMBL429392 | N,N'-(2,2'-(7,7'-(propane-1,3-diylbis(oxy))bis(naphthalene-7,1-diyl))bis(ethane-2,1-diyl))diacetamide | N-[2-(7-{3-[8-(2-Acetylamino-ethyl)-naphthalen-2-yloxy]-propoxy}-naphthalen-1-yl)-ethyl]-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C31H34N2O4 |
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| Mol. Mass. | 498.6127 |
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| SMILES | CC(=O)NCCc1cccc2ccc(OCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 |
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| Structure | 
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