| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
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| Ligand | BDBM28798 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_154051 (CHEMBL760856) |
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| EC50 | 1300±n/a nM |
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| Citation |  Ebdrup, S; Pettersson, I; Rasmussen, HB; Deussen, HJ; Frost Jensen, A; Mortensen, SB; Fleckner, J; Pridal, L; Nygaard, L; Sauerberg, P Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar. J Med Chem46:1306-17 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor gamma |
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| Name: | Peroxisome proliferator-activated receptor gamma |
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| Synonyms: | NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2 |
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| Type: | Nuclear Receptor |
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| Mol. Mass.: | 57613.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37231 |
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| Residue: | 505 |
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| Sequence: | MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL
LQVIKKTETDMSLHPLLQEIYKDLY
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| BDBM28798 |
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| n/a |
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| Name | BDBM28798 |
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| Synonyms: | (2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)phenyl]ethoxy}phenyl)propanoic acid | AZ 242 | Galida | tesaglitazar |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24O7S |
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| Mol. Mass. | 408.465 |
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| SMILES | CCO[C@@H](Cc1ccc(OCCc2ccc(OS(C)(=O)=O)cc2)cc1)C(O)=O |r| |
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| Structure | 
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