| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
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| Ligand | BDBM50127222 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154532 |
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| EC50 | >10000±n/a nM |
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| Citation |  Sznaidman, ML; Haffner, CD; Maloney, PR; Fivush, A; Chao, E; Goreham, D; Sierra, ML; LeGrumelec, C; Xu, HE; Montana, VG; Lambert, MH; Willson, TM; Oliver, WR; Sternbach, DD Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity. Bioorg Med Chem Lett13:1517-21 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor gamma |
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| Name: | Peroxisome proliferator-activated receptor gamma |
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| Synonyms: | Nr1c3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG_MOUSE | Pparg |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57593.55 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1453700 |
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| Residue: | 505 |
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| Sequence: | MGETLGDSPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKNLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQL
LHVIKKTETDMSLHPLLQEIYKDLY
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| BDBM50127222 |
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| n/a |
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| Name | BDBM50127222 |
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| Synonyms: | CHEMBL38508 | GW-0742 | {4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethylsulfanyl]-2-methyl-phenoxy}-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17F4NO3S2 |
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| Mol. Mass. | 471.488 |
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| SMILES | Cc1nc(sc1CSc1ccc(OCC(O)=O)c(C)c1)-c1ccc(c(F)c1)C(F)(F)F |
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| Structure | 
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