| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50127609 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_85521 (CHEMBL697132) |
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| EC50 | >0.000100±n/a nM |
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| Citation |  Kazuta, Y; Hirano, K; Natsume, K; Yamada, S; Kimura, R; Matsumoto, S; Furuichi, K; Matsuda, A; Shuto, S Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure. J Med Chem46:1980-8 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40115.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 359 |
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| Sequence: | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
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| BDBM50127609 |
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| n/a |
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| Name | BDBM50127609 |
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| Synonyms: | C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine | CHEMBL302231 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H11N3 |
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| Mol. Mass. | 137.1823 |
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| SMILES | NC[C@@H]1C[C@H]1c1cnc[nH]1 |
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| Structure | 
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