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TargetGag-Pol polyprotein [489-587]
LigandBDBM50127970
Substrate/Competitorn/a
Meas. Tech.ChEMBL_159453 (CHEMBL766798)
IC50 0.062000±n/a nM
Citation Lu, ZRaghavan, SBohn, JCharest, MStahlhut, MWRutkowski, CASimcoe, ALOlsen, DBSchleif, WACarella, AGabryelski, LJin, LLin, JHEmini, EChapman, KTata, JR Design and synthesis of highly potent HIV protease inhibitors with activity against resistant virus. Bioorg Med Chem Lett13:1821-4 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50127970
n/a
NameBDBM50127970
Synonyms:3-[(1R,4S)-2-Hydroxy-4-((1S,2R)-2-hydroxy-indan-1-ylcarbamoyl)-5-phenyl-pentanoyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,6-dimethyl-benzylamide | CHEMBL298189
TypeSmall organic molecule
Emp. Form.C36H43N3O5S
Mol. Mass.629.809
SMILESCc1cccc(C)c1CNC(=O)[C@H]1N(CSC1(C)C)C(=O)[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12
Structure
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