| Reaction Details |
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 | Report a problem with these data |
| Target | Hypoxanthine-guanine phosphoribosyltransferase |
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| Ligand | BDBM50128865 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90368 (CHEMBL697044) |
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| Ki | 6700±n/a nM |
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| Citation |  Medrano, FJ; Wenck, MA; Engel, JC; Craig, SP Analysis of 6-(2,2-Dichloroacetamido)chrysene interaction with the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi. J Med Chem46:2548-50 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hypoxanthine-guanine phosphoribosyltransferase |
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| Name: | Hypoxanthine-guanine phosphoribosyltransferase |
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| Synonyms: | HGPRT | HGPRTase | HPRT | HPRT1 | HPRT_HUMAN | Hypoxanthine-guanine phosphoribosyltransferase | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) |
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| Type: | Protein |
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| Mol. Mass.: | 24579.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00492 |
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| Residue: | 218 |
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| Sequence: | MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH
HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD
DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG
FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
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| BDBM50128865 |
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| n/a |
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| Name | BDBM50128865 |
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| Synonyms: | 6-Nitro-chrysene | CHEMBL82858 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H11NO2 |
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| Mol. Mass. | 273.2854 |
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| SMILES | [O-][N+](=O)c1cc2c3ccccc3ccc2c2ccccc12 |
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| Structure | 
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