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TargetHypoxanthine-guanine phosphoribosyltransferase
LigandBDBM50128869
Substrate/Competitorn/a
Meas. Tech.ChEMBL_90370 (CHEMBL697046)
Ki 16000±n/a nM
Citation Medrano, FJWenck, MAEngel, JCCraig, SP Analysis of 6-(2,2-Dichloroacetamido)chrysene interaction with the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi. J Med Chem46:2548-50 (2003) [PubMed]  Article
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Hypoxanthine-guanine phosphoribosyltransferase
Name:Hypoxanthine-guanine phosphoribosyltransferase
Synonyms:HGPRT | HGPRTase | HPRT | HPRT1 | HPRT_HUMAN | Hypoxanthine-guanine phosphoribosyltransferase | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
Type:Protein
Mol. Mass.:24579.61
Organism:Homo sapiens (Human)
Description:P00492
Residue:218
Sequence:
MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH
HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD
DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG
FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
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BDBM50128869
n/a
NameBDBM50128869
Synonyms:2,2-Dichloro-N-chrysen-6-yl-acetamide | CHEMBL88057
TypeSmall organic molecule
Emp. Form.C20H13Cl2NO
Mol. Mass.354.229
SMILESClC(Cl)C(=O)Nc1cc2c3ccccc3ccc2c2ccccc12
Structure
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