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TargetHypoxanthine-guanine phosphoribosyltransferase
LigandBDBM50128867
Substrate/Competitorn/a
Meas. Tech.ChEMBL_90369 (CHEMBL697045)
Ki 13900±n/a nM
Citation Medrano, FJWenck, MAEngel, JCCraig, SP Analysis of 6-(2,2-Dichloroacetamido)chrysene interaction with the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi. J Med Chem46:2548-50 (2003) [PubMed]  Article
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Hypoxanthine-guanine phosphoribosyltransferase
Name:Hypoxanthine-guanine phosphoribosyltransferase
Synonyms:HGPRT | HGPRTase | HPRT | HPRT1 | HPRT_HUMAN | Hypoxanthine-guanine phosphoribosyltransferase | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
Type:Protein
Mol. Mass.:24579.61
Organism:Homo sapiens (Human)
Description:P00492
Residue:218
Sequence:
MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH
HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD
DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG
FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
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BDBM50128867
n/a
NameBDBM50128867
Synonyms:3,5-diphenyl-4'-methyl-2-nitrobiphenyl | CHEMBL87526
TypeSmall organic molecule
Emp. Form.C25H19NO2
Mol. Mass.365.4239
SMILESCc1ccc(cc1)-c1cc(cc(-c2ccccc2)c1[N+]([O-])=O)-c1ccccc1
Structure
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