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TargetHigh affinity immunoglobulin epsilon receptor subunit alpha
LigandBDBM50130413
Substrate/Competitorn/a
Meas. Tech.ChEMBL_68796 (CHEMBL683435)
IC50 114000±n/a nM
Citation Buku, AMendlowitz, MCondie, BAPrice, JA Histamine-releasing activity and binding to the FcepsilonRI alpha human mast cell receptor subunit of mast cell degranulating peptide analogues with alanine substitutions. J Med Chem46:3008-12 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
High affinity immunoglobulin epsilon receptor subunit alpha
Name:High affinity immunoglobulin epsilon receptor subunit alpha
Synonyms:FCE1A | FCER1A | FCERA_HUMAN | Fc-epsilon RI-alpha | FcERI | High affinity immunoglobulin epsilon receptor subunit alpha | IgE Fc receptor subunit alpha | IgE Fc receptor, alpha-subunit
Type:PROTEIN
Mol. Mass.:29595.99
Organism:Homo sapiens (Human)
Description:ChEMBL_68795
Residue:257
Sequence:
MAPAMESPTLLCVALLFFAPDGVLAVPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVS
STKWFHNGSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAE
VVMEGQPLFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTGKV
WQLDYESEPLNITVIKAPREKYWLQFFIPLLVVILFAVDTGLFISTQQQVTFLLKIKRTR
KGFRLLNPHPKPNPKNN
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  Blast E-value cutoff:
BDBM50130413
n/a
NameBDBM50130413
Synonyms:CHEMBL411579 | IKCNCKRHVIKPHICRKICGKN-NH2
TypeSmall organic molecule
Emp. Form.C110H196N40O24S4
Mol. Mass.2591.247
SMILESCC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(N)=O
Structure
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