| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50130617 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_146920 (CHEMBL757508) |
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| Ki | 46±n/a nM |
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| Citation |  Okada, Y; Tsuda, Y; Fujita, Y; Yokoi, T; Sasaki, Y; Ambo, A; Konishi, R; Nagata, M; Salvadori, S; Jinsmaa, Y; Bryant, SD; Lazarus, LH Unique high-affinity synthetic mu-opioid receptor agonists with central- and systemic-mediated analgesia. J Med Chem46:3201-9 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40465.04 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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| BDBM50130617 |
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| n/a |
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| Name | BDBM50130617 |
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| Synonyms: | 2-Amino-N-{6-[2-amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-hexyl}-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionamide | CHEMBL108808 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H42N4O4 |
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| Mol. Mass. | 498.6575 |
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| SMILES | Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCCCNC(=O)[C@H](N)Cc1c(C)cc(O)cc1C |
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| Structure | 
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