Reaction Details |
| Report a problem with these data |
Target | 5-hydroxytryptamine receptor 2A |
---|
Ligand | BDBM50131085 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_2632 |
---|
Ki | 1.3±n/a nM |
---|
Citation | Peddi, S; Roth, BL; Glennon, RA; Westkaemper, RB Ring substituted analogues of 5-aminomethyl-10,11-dihydro-dibenzo[a,d]cycloheptene (AMDH): potential modes of binding to the 5-HT(2A) receptor. Bioorg Med Chem Lett13:2565-8 (2003) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
5-hydroxytryptamine receptor 2A |
---|
Name: | 5-hydroxytryptamine receptor 2A |
Synonyms: | 5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 52852.05 |
Organism: | Rattus norvegicus (rat) |
Description: | Rat cortex membranes 5-HT2A receptors. |
Residue: | 471 |
Sequence: | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
|
|
|
BDBM50131085 |
---|
n/a |
---|
Name | BDBM50131085 |
Synonyms: | 3-Bromo-9-aminomethyl-9,10-dihydroanthracene | C-(3-Bromo-9,10-dihydro-anthracen-9-yl)-methylamine | CHEMBL85882 |
Type | Small organic molecule |
Emp. Form. | C15H14BrN |
Mol. Mass. | 288.182 |
SMILES | NCC1c2ccccc2Cc2cc(Br)ccc12 |
Structure |
|