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TargetPeptide deformylase, mitochondrial
LigandBDBM50131308
Substrate/Competitorn/a
Meas. Tech.ChEBML_154178
IC50 70±n/a nM
Citation Davies, SJAyscough, APBeckett, RPBragg, RAClements, JMDoel, SGrew, CLaunchbury, SBPerkins, GMPratt, LMSmith, HKSpavold, ZMThomas, SWTodd, RSWhittaker, M Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1' side chain. Bioorg Med Chem Lett13:2709-13 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Peptide deformylase, mitochondrial
Name:Peptide deformylase, mitochondrial
Synonyms:DEFM_HUMAN | PDF | PDF1A | Peptide deformylase mitochondrial | Peptide deformylase, mitochondrial | Polypeptide deformylase
Type:PROTEIN
Mol. Mass.:27023.25
Organism:Homo sapiens (Human)
Description:ChEMBL_154318
Residue:243
Sequence:
MARLWGALSLWPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPP
EPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPR
QVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLA
CVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMK
VND
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  Blast E-value cutoff:
BDBM50131308
n/a
NameBDBM50131308
Synonyms:(S)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((S)-1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide | CHEMBL93332
TypeSmall organic molecule
Emp. Form.C16H31N3O4
Mol. Mass.329.435
SMILESCCCC[C@@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C
Structure
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