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Target5-hydroxytryptamine receptor 2C
LigandBDBM50131665
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2839 (CHEMBL621525)
Ki 1.1±n/a nM
Citation Chambers, JJParrish, JCJensen, NHKurrasch-Orbaugh, DMMarona-Lewicka, DNichols, DE Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT(2A/2C) receptor ligands. J Med Chem46:3526-35 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 2C
Name:5-hydroxytryptamine receptor 2C
Synonyms:5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
Type:Enzyme
Mol. Mass.:51935.10
Organism:Rattus norvegicus (Rat)
Description:P08909
Residue:460
Sequence:
MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALS
IVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYV
WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVW
AISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIY
VLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRG
TMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGY
VCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRH
TNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
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  Blast E-value cutoff:
BDBM50131665
n/a
NameBDBM50131665
Synonyms:C-(8-Bromo-6-methoxy-4,5-dihydro-3H-naphtho[1,8-bc]furan-5-yl)-methylamine | CHEMBL116940
TypeSmall organic molecule
Emp. Form.C13H14BrNO2
Mol. Mass.296.16
SMILESCOc1cc(Br)c2occ3CC[C@@H](CN)c1c23
Structure
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