| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50131891 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_33743 (CHEMBL647058) |
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| Ki | 0.094±n/a nM |
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| Citation |  Boschi, D; Tron, GC; Di Stilo, A; Fruttero, R; Gasco, A; Poggesi, E; Motta, G; Leonardi, A New potential uroselective NO-donor alpha1-antagonists. J Med Chem46:3762-5 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_HUMAN | ADRA1A | ADRA1C | Adrenergic alpha1A | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha adrenergic receptor 1a | Alpha-1C adrenergic receptor | Alpha-adrenergic receptor 1c | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 | adrenergic Alpha1C |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 51511.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35348 |
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| Residue: | 466 |
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| Sequence: | MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
APAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTL
HPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCT
TARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV
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| BDBM50131891 |
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| n/a |
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| Name | BDBM50131891 |
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| Synonyms: | 3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid (3-{4-[2-(3-nitrooxy-propoxy)-phenyl]-piperazin-1-yl}-propyl)-amide | CHEMBL338029 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H36N4O7 |
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| Mol. Mass. | 600.6615 |
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| SMILES | Cc1c(oc2c(cccc2c1=O)C(=O)NCCCN1CCN(CC1)c1ccccc1OCCCO[N+]([O-])=O)-c1ccccc1 |
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| Structure | 
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