Reaction Details |
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Target | 5-hydroxytryptamine receptor 5A |
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Ligand | BDBM50132093 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_3595 (CHEMBL618080) |
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Ki | 435±n/a nM |
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Citation | Khorana, N; Smith, C; Herrick-Davis, K; Purohit, A; Teitler, M; Grella, B; Dukat, M; Glennon, RA Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors. J Med Chem46:3930-7 (2003) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 5A |
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Name: | 5-hydroxytryptamine receptor 5A |
Synonyms: | 5-HT-5 | 5-HT-5A | 5-HT5 | 5-HT5a | 5-hydroxytryptamine receptor 5A | 5HT5A_MOUSE | 5ht5a | Htr5a | Serotonin 5a (5-HT5a) receptor | Serotonin receptor 5A |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 40749.33 |
Organism: | MOUSE |
Description: | 5-HT5 0 MOUSE::P30966 |
Residue: | 357 |
Sequence: | MDLPVNLTSFSLSTPSSLEPNRSLDTEVLRPSRPFLSAFRVLVLTLLGFLAAATFTWNLL
VLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMILLTWALSTVISLAPLLFG
WGETYSEPSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAAKFRMGSRKTNSVS
PVPEAVEVKNATQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFP
FFVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
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BDBM50132093 |
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n/a |
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Name | BDBM50132093 |
Synonyms: | 5-Methyl-2-(6-phenyl-hexyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | CHEMBL125361 |
Type | Small organic molecule |
Emp. Form. | C24H30N2 |
Mol. Mass. | 346.5084 |
SMILES | Cn1c2CCN(CCCCCCc3ccccc3)Cc2c2ccccc12 |
Structure |
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