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Target5-hydroxytryptamine receptor 5A
LigandBDBM50132091
Substrate/Competitorn/a
Meas. Tech.ChEMBL_3595 (CHEMBL618080)
Ki 95±n/a nM
Citation Khorana, NSmith, CHerrick-Davis, KPurohit, ATeitler, MGrella, BDukat, MGlennon, RA Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors. J Med Chem46:3930-7 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 5A
Name:5-hydroxytryptamine receptor 5A
Synonyms:5-HT-5 | 5-HT-5A | 5-HT5 | 5-HT5a | 5-hydroxytryptamine receptor 5A | 5HT5A_MOUSE | 5ht5a | Htr5a | Serotonin 5a (5-HT5a) receptor | Serotonin receptor 5A
Type:Enzyme Catalytic Domain
Mol. Mass.:40749.33
Organism:MOUSE
Description:5-HT5 0 MOUSE::P30966
Residue:357
Sequence:
MDLPVNLTSFSLSTPSSLEPNRSLDTEVLRPSRPFLSAFRVLVLTLLGFLAAATFTWNLL
VLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMILLTWALSTVISLAPLLFG
WGETYSEPSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAAKFRMGSRKTNSVS
PVPEAVEVKNATQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFP
FFVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50132091
n/a
NameBDBM50132091
Synonyms:2-[4-(4-Fluoro-phenyl)-butyl]-5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | CHEMBL341506
TypeSmall organic molecule
Emp. Form.C22H25FN2
Mol. Mass.336.4457
SMILESCn1c2CCN(CCCCc3ccc(F)cc3)Cc2c2ccccc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: