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Target5-HT5
LigandBDBM50132090
Substrate/Competitorn/a
Meas. Tech.ChEMBL_3595
Ki 98±n/a nM
Citation Khorana NSmith CHerrick-Davis KPurohit ATeitler MGrella BDukat MGlennon RA Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors. J Med Chem 46:3930-7 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-HT5
Name:5-HT5
Synonyms:5-HT-5 | 5-HT-5A | 5-HT5a | 5-hydroxytryptamine receptor 5A | Serotonin 5a (5-HT5a) receptor | Serotonin receptor 5A
Type:Enzyme Catalytic Domain
Mol. Mass.:40749.33
Organism:MOUSE
Description:5-HT5 0 MOUSE::P30966
Residue:357
Sequence:
MDLPVNLTSFSLSTPSSLEPNRSLDTEVLRPSRPFLSAFRVLVLTLLGFLAAATFTWNLL
VLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMILLTWALSTVISLAPLLFG
WGETYSEPSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAAKFRMGSRKTNSVS
PVPEAVEVKNATQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFP
FFVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50132090
n/a
NameBDBM50132090
Synonyms:2-[3-(4-Fluoro-phenoxy)-propyl]-8-methoxy-5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | CHEMBL128185
TypeSmall organic molecule
Emp. Form.C22H25FN2O2
Mol. Mass.368.4445
SMILESCOc1ccc2n(C)c3CCN(CCCOc4ccc(F)cc4)Cc3c2c1
Structure
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