| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor gamma |
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| Ligand | BDBM50132580 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_196011 |
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| Ki | >10000±n/a nM |
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| Citation |  Gernert, DL; Ajamie, R; Ardecky, RA; Bell, MG; Leibowitz, MD; Mais, DA; Mapes, CM; Michellys, PY; Rungta, D; Reifel-Miller, A; Tyhonas, JS; Yumibe, N; Grese, TA Design and synthesis of fluorinated RXR modulators. Bioorg Med Chem Lett13:3191-5 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor gamma |
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| Name: | Retinoic acid receptor gamma |
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| Synonyms: | NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50345.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1458016 |
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| Residue: | 454 |
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| Sequence: | MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
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| BDBM50132580 |
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| n/a |
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| Name | BDBM50132580 |
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| Synonyms: | (2E,4E,6E)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy)-phenyl]-6-fluoro-3-methyl-octa-2,4,6-trienoic acid | CHEMBL111217 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H33F3O3 |
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| Mol. Mass. | 438.5229 |
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| SMILES | C\C(\C=C\C(\F)=C(\C)c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C)=C/C(O)=O |
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| Structure | 
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