| Reaction Details |
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 | Report a problem with these data |
| Target | Progesterone receptor |
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| Ligand | BDBM50133133 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_159730 (CHEMBL766187) |
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| Ki | 1.5±n/a nM |
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| Citation |  Zhi, L; Tegley, CM; Pio, B; Edwards, JP; Motamedi, M; Jones, TK; Marschke, KB; Mais, DE; Risek, B; Schrader, WT 5-benzylidene-1,2-dihydrochromeno[3,4-f]quinolines as selective progesterone receptor modulators. J Med Chem46:4104-12 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Progesterone receptor |
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| Name: | Progesterone receptor |
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| Synonyms: | NR3C3 | Nuclear receptor subfamily 3 group C member 3 | PGR | PR | PRGR_HUMAN | progesterone |
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| Type: | Protein |
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| Mol. Mass.: | 98979.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06401 |
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| Residue: | 933 |
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| Sequence: | MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLF
PRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLA
PSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAA
AHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGK
PRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTV
MDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPD
CAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLG
PPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPC
KAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPP
YLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHN
YLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPV
GVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQ
LGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAP
DLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQ
FEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRA
LSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
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| BDBM50133133 |
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| n/a |
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| Name | BDBM50133133 |
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| Synonyms: | 7-Fluoro-2,2,4-trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene | CHEMBL337856 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H24FNO |
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| Mol. Mass. | 397.484 |
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| SMILES | CC1=CC(C)(C)Nc2ccc3-c4cccc(F)c4O\C(=C/c4ccccc4C)c3c12 |t:1| |
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| Structure | 
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