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TargetProstaglandin E2 receptor EP3 subtype
LigandBDBM50134513
Substrate/Competitorn/a
Meas. Tech.ChEBML_158318
Ki 52.0±n/a nM
Citation Gallant, MBelley, MCarrière, MCChateauneuf, ADenis, DLachance, NLamontagne, SMetters, KMSawyer, NSlipetz, DTruchon, JFLabelle, M Structure-activity relationship of triaryl propionic acid analogues on the human EP3 prostanoid receptor. Bioorg Med Chem Lett13:3813-6 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor EP3 subtype
Name:Prostaglandin E2 receptor EP3 subtype
Synonyms:PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor
Type:Enzyme
Mol. Mass.:43335.03
Organism:Homo sapiens (Human)
Description:P43115
Residue:390
Sequence:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
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  Blast E-value cutoff:
BDBM50134513
n/a
NameBDBM50134513
Synonyms:CHEMBL124675 | {2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenylamino}-acetic acid
TypeSmall organic molecule
Emp. Form.C25H21NO3S
Mol. Mass.415.504
SMILESOC(=O)CNc1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1
Structure
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